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Citations and Validations
Growth Hormone Releasing Factor
Growth hormone-releasing hormone (GHRH) is not widely distributed throughout the brain and is found only in the hypothalamus. The secretion of GHRH increases in response to physical and emotional stress, and its secretion is blocked by a powerful hypothalamic neurohormone called somatostatin. The secretion of GHRH is also inhibited by insulin-like growth factors, which are generated when tissues are exposed to growth hormone itself.