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  • Ac-Nle-cyclo(-Asp-His-D-Phe-Arg-Trp-Lys)Bremelanotide is a melanocortin receptor agonist shown to improve female sexual function in females suffering from sexual dysfunction.
  • Ala-Tyr-Ile-Gln-Asn-HomoCys-Pro-Lys-Gly-NH2(Ala&HomoCysSideChainThioesterBridge)N/A
  • Arg-Gly-Asp-CysFilms formed from 1,12-diphosphonododecane were treated with zirconium tetra (tert-butoxide) to give surface Zr complex species; derivatives of these surface complexes are stable to hydrolysis under physiological conditions and are mechanically strong. The cell attractive peptide derivative ARG-GLY-ASP-CYS, RGDC can be bound to these surface Zr alkoxide complexes through (maleimido) alkylcarboxylate intermediates. Surfaces modified with RGDC were shown to be effective for osteoblast binding and proliferation.
  • AEThis peptide consists of two amino acids, Ala and Glu, and is provided at >95% purity.
  • ADThis peptide consists of two amino acids, Ala and Asp and is provided at >95% purity.
  • AAAla-Ala is a stereospecific model dipeptide used to study the effects of protonation on peptide conformation in physiochemisty.
  • AQThis peptide consists of two amino acids, Ala and Gln and is provided at >95% purity.
  • ALThis peptide consists of two amino acids, Ala and Leu, and is provided at >95% purity.
  • AHThis peptide consists of two amino acids, Ala and His, and is provided at >95% purity.
  • AGThis peptide consists of two amino acids, Ala and Gly, and is provided at >95% purity.
  • ARThis peptide consists of two amino acids, Ala and Arg, and is provided at >95% purity.
  • APThis peptide consists of two amino acids, Ala and Pro, and is provided at >95% purity.
  • Arg-Gly-Glu-SerArg-Gly-Glu-Ser is a RGD-related peptide and a control for the RGDS ihibitory activity on fibrinogen binding to activated platelets
  • AstressinAstressin is an amino-terminal truncated analog of CRF that retains high affinity binding to the extracellular domain of the receptor and is believed to act as a neutral competitive antagonist of receptor activation.
  • ApaminApamin, a bee venom polypeptide, blocks specifically the Ca2+-dependent K+ channels that are not blocked by tetraethylammonium chloride in muscle cells. Apamin is a highly specific compound that tightly binds to the Ca2+ slow channels, thus blocking the slow APs in heart muscle. In addition, quinidine antagonizes the apamin binding on the slow APs.
  • A-779A-779 is a potent and selective Ang (1-7) antagonist. A-779 antagonizes several actions of Ang (1-7), including A-779's antidiurectic effect and the changes in MAP produced by Ang (1-7) microinjection into the dorsomedial or ventrolateral medulla.
  • AxltidePeptide sequence (KKSRGDYMTMQIG) is based on the mouse Insulin receptor substrate 1 (amino acid 979-989).
  • AHK-CUGHK-Cu, Copper Peptide, is a naturally occurring human tri-peptide. In plasma, the level of GHK-Cu is about 200 ng/ml at age 20. By the age of 60, the level drops to 80 ng/ml. Scientific studies conducted in different research laboratories around the world have established that human tri-peptide GHK-Cu possesses a plethora of biological actions including activation of wound healing, attraction of immune cells, antioxidant and anti-inflammatory effects, stimulation of collagen and glycosaminoglycan synthesis in skin fibroblasts and promotion of blood vessels growth. Recent studies indicate its important role in stem cell biology and anti-tumor defense. Since GHK-Cu plays an important role in skin biology, it is widely used in cosmetics as a reparative and anti-aging ingredient. The levels of GHK decrease as you age.
  • Angiotensin II (1-4), humanAngiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure. Angiotensin also potentiates the release of norepinephrine by a direct action on postganglionic sympathetic fibers.
  • Amylin (20 - 29), humanAmylin is produced in the pancreas beta cells and coreleased with insulin. Amylin's amino acid sequence shows great homology with CGRP. Amylin has been shown to reverse insulin inhibition of hepatic gluconeogenesis and to inhibit muscle uptake of glucose.
  • Acetyl CarnosineN-Acetyl-L-carnosine has been studied as a measure to counteract UV-induced immunosuppression. N-acetyl-L-Carnosine (NAC) is a natural imidazole-containing dipeptide that has antioxidant activities in cells, particularly against lipid peroxidation. Formulations containing NAC may prevent or resolve cataracts when added to the eyes of animals, presumably through the conversion of NAC to another antioxidant, carnosine. NAC and related dipeptides, delivered in specific formulations, may also have protective effects for skin.
  • Adrenocorticotropic Hormone (ACTH) (1-39), humanAdrenocorticotropic hormones (ACTH). ACTH stimulates the adrenal cortex and the secretion of glucocorticoids such as cortisol. Another name for ACTH is corticotropin.
  • Adrenocorticotropic Hormone (ACTH) (1-24), humanAdrenocorticotropic hormones (ACTH). ACTH stimulates the adrenal cortex and the secretion of glucocorticoids such as cortisol. Another name for ACTH is corticotropin. ACTH (1-24) activates G proteins.
  • ACTH (7 - 38), humanCorticotropin-inhibiting peptide (CIP), the 7-38 fragment of human ACTH (1-39), is known to act as an antagonist of ACTH receptors. It does not have any corticosteroidogenic activity.
  • ACTH (1 - 17)Adrenocorticotropic hormones (ACTH). ACTH stimulates the adrenal cortex and the secretion of glucocorticoids such as cortisol.
  • Adrenomedullin (AM) (13-52), humanAdrenomedullin (13-52) is a 40 amino acid peptide with one intramolecular disulfide bridge, Adrenomedullin (13-52) is a high affinity ligand for the adrenomedullin receptor.
  • Adrenomedullin (AM) (1-52), humanAdrenomedullin (1-52) is a potent hypotensive peptide hormone with some structural similarity to calcitonin gene-related peptide. Adrenomedullin (1-52) has vasodilatory properties.
  • Amylin (8-37), amide, ratAmylin is a 37-aa peptide produced in the pancreatic beta-cell secretory granules and Amylin is co-released with insulin. Amylin has specific binding sites in the CNS and Amylin may regulate gastric emptying and influence carbohydrate metabolism.
  • Amylin, felineAmylin is produced in the pancreas beta cells and coreleased with insulin. Amylin's amino acid sequence shows great homology with CGRP. Amylin has been shown to reverse insulin inhibition of hepatic gluconeogenesis and to inhibit muscle uptake of glucose.
  • Angiotensin II, humanAngiotensin II (ANG II) is an important physiological effector of blood pressure and volume regulation through vasoconstriction, sodium uptake, the release of aldosterone, and the stimulation of thirst. Angiotensin II is mediated by its interaction with, Angiotensin II type 1 membrane receptors.
  • Angiotensinogen (1-14), humanAngiotensinogen is a serum globulin formed by the liver that is cleaved by renin to form angiotensin I. Angiotensinogen is also called angiotensin precursor.
  • Angiotensin I, humanAngiotensin I is a putative neurotransmitter. Angiotensin I is the precursor of angiotensin II and of angiotensin fragment 1-7, which are the hormones involved in regulation of fluid volume and the release of aldosterone.
  • Angiotensin (1 - 7)Endogenous peptide fragment. Induces vasorelaxation through release of NO and prostaglandins, perhaps through activation of a non-AT1, non-AT2 receptor, Mas. Counteracts the vasoconstrictive and proliferative effects of angiotensin II and stimulates vasopressin (anti-diuretic hormone) release in vivo.
  • Angiotensin (1 - 9)Endogenous peptide fragment, function in cardiac and vascular remodelling.
  • Annexin 1 (ANXA - 1, Ac 2 - 26)This acetylated peptide is amino acids 2 to 28 N-terminus fragment of Annexin 1 (ANXA1). ANXA1, previously referred to as lipocortin 1 or LC1, is a member of the annexin superfamily that has potent leukocyte antimigratory activity. This fragment, as well as the full-length ANXA1, may significantly reduce polymorphonuclear leukocyte (PMN) influx in mice. ANXA1 and ANXA1 mimetics, such as Ac (2-12), inhibit recruitment of neutrophils in acute and chronic inflammation. This peptide is able to inhibit neutrophil extravasation.
  • Apidaecin IBApidaecin IB is an insect antimicrobial peptide showing a significant sequence homology and a common mechanism of action with drosocin, but is devoid of any pore-forming activity.
  • Antioxidant peptide AThis is a antioxidant peptide.
  • Autocamtide 2-amideUse as the substrate (100uM final concentration) for CaM kinase family assays.
  • AH1 Sequence (6 - 14)This AH1 sequence (amino acids 6 to 14) is the H2-Ld-restricted epitope derived from gp-70 (endogenous retroviral gene product envelope glycoprotein 70), which is expressed in CT26 (colon carcinoma cells) and numerous other tumor cell lines. AH
  • Apolipoprotein KV domain (67 - 77)This peptide is derived from Kringle5-like domain (termed KV) in human Apolipoprotein amino acid residues 67-77. KV11 inhibits angiogenesis in vitro and in vivo.
  • Antennapedia Peptide, acidThis peptide is the homeodomain of the Drosophila homeoprotein Antennapaedia (residues 43-58, commonly named penetratin, RQIKIWFQNRRMKWKK),provides novel insights into the fundamental mechanisms of translocation across biological membranes.
  • Atrial Natriuretic Peptide (ANP) (1-28), ratAtrial natriuretic peptide (ANP) is synthesized in myoendocrine cells of the heart from which it is released into the circulation. Atrial natriuretic peptide (ANP) exerts natriuretic, diuretic, and vasodilatory effects through stimulation of guanylate cyclase-linked NPR-A receptors. Atrial natriuretic peptide (ANP) plays an important role in blood volume and blood pressure homeostasis.
  • Atrial Natriuretic Peptide (ANP) (1-28), human, porcineAtrial natriuretic peptide (ANP), a stimulator of particulate guanylate cyclase, has been found to protect against reoxygenation-induced hypercontracture in isolated cardiomyocytes by increasing cyclic guanosine monophosphate synthesis; ANP also contributes to stimulation of lipolysis during repeated bouts of exercise and in the control of lipolysis during exercise.
  • Adipokinetic Hormone (AKH), locustAdipokinetic hormones (AKHs) are metabolic neuropeptides, mediating mobilization of energy substrates from the fat body in many insects. They bring on the release of diglycerides and then stimulate the flight muscles to use them as an energy source. There are other types of active peptides structurally related to AKH. These peptides are eight to ten amino acid residues long.
  • Abz-FR-K (Dnp)-P-OHExcellent angiotensin I-converting enzyme (ACE) substrate with a Km value of 4.0 μM and a kcat value of 210s-1.
  • Adrenomedullin (1 - 50),Adrenomedullin (AM), an ubiquitous regulatory peptide with different actions, is known to be elevated in different clinical situations, including diabetes mellitus (DM), but its potential role in the pathogenesis of diabetic vascular complications is not clear.
  • Autocamtide 2The native peptide Autocamtide 2 (KKALRRQETVDAL) is a highly selective substrate for Ca2+/calmodulin-dependent protein kinase (CaMK). The peptide Autocamtide 2 contains the sequence around the autophosphorylation site in the autoinhibitory domain of calmodulin-dependent protein kinase II (CaM kinase II). The fluorescent and biotinylated peptides are used to design assays for CaMKs.
  • Abl Cytosolic SubstrateThis synthetic peptide is a substrate for Abelson tyrosine kinase (Abl ).
  • AMARA peptideAMARA peptide is a minimal substrate of several members of the protein kinases family. It consists of the phosphorylation site for AMP-activated Protein Kinase (AMPK). AMARA peptide may be employed in the applications to measure AMPK-related kinase activity.
  • Alarelin AcetateAlarelin acetate is a synthetic Gonadotrophin-releasing hormone agonist. It is the acetate form of a hypothalamic peptide. It is a potent LH-RH agonist in rats and mice. It reversibly delays sexual maturation in rats, stimulates spawning activity in fish. It could inducte ovulation and is used to treat endmometriosis. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands.
  • Angiotensin AcetateAngiotensin peptides exhibit pressor (vasoconstrictive) activity through binding of the angiotensin II type 1 (AT1) receptor, increasing blood pressure and volume.
  • Argireline AcetateArgireline is the trade name for Acetyl Hexapeptide-3, a synthetic anti-aging cosmetic peptide derived from natural proteins. It is a peptide chain made up of amino acids. Argireline has been shown in research studies to help decrease the visible effects of aging by helping to reduce the deep wrinkles and lines that occur around the forehead and eyes. Resultanty, a large number of cosmetics companies include Argireline in the formulation of their anti-aging products. These products include creams, lotions, serums, body milks, eye creams, gels and emulsions.
  • Argpressin AcetateArgpressin Acetate is a neurohypophysial hormone found in most mammals. It acts as a neurotransmitter at synapses in the brain, increases [Ca2+]I in cultured rat hippocampal neurons.
  • Atosiban AcetateAtosiban acetate is a competitive oxytocin and vasopressin antagonist by exhibiting high affinity for both receptors. It is used to treat preterm labors.
  • Aviptadil AcetateVIP, a 28-amino acid peptide belonging to the secretin-glucagon-CRF family, is widely distributed in the central and peripheral nervous systems. Acting both as a neurotransmitter and as a hormone, VIP is involved in a wide variety of biological activities, including vaso- and bronchodilation, smooth muscle relaxation, and stimulation of secretion. An injectable formulation of this peptide in combination with the adrenergic drug phentolamine is expected to provide a new and effective alternative for erectile dysfunction patients.
  • Abarelix AcetateAbarelix acetate is a synthetic peptide gonadotropin releasing hormone receptor (GnRH) antagonist
  • Argireline (Acetyl Hexapeptide-3)Argireline is a syntheticpeptide as a fragment of SNAP-25, a substrate of Botulinum toxin (Botox). for anti-wrinkle cosmetics ingredient.
  • Ac-KQKLR-AMCAcetyl-KQKLR-AMC, fluorogenic substrate for cathepsin S.
  • Ac-FR-AMCN/A
  • Ac-YVAD-AFCAc-YVAD-AFC is a substrate whose amino acids YVAD have been shown to be a preferred cleavage site for caspase-1 and -4.1,2 Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.
  • Ac-WEHD-AFCAc-WEHD-AFC is a fluorogenic substrate that can be cleaved by group I caspases (caspase-1, -4, and -5).1 Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.
  • Ac-AAPF-pNAAc-AAPF-pNA, chromogenic substrate for chymotrypsin and an excellent substrate for proteinase yscD (saccharolysin).
  • Ac-DEVD-pNADuring apoptosis, activated caspase-3 cleaves several substrates, including poly(ADP-ribose) polymerase, which it specifically targets at the amino sequence DEVD. Ac-DEVD-pNA is a para-nitro aniline chromophore cleaved by caspases (Km = 18, 11, 32, 180, and 12 µM for caspases-1, -3, -4, -6, and -7, respectively). It is not cleaved by caspase-2.2 Cleavage is monitored colorimetrically at 405 nm.
  • Ala-Pro-Arg-Lys-Gln-Leu-Ala-Thr-Lys-Ala-Ala-Arg-Lys(Me)-Ser-AlaPro-Ala-Thr-Gly-Gly-Val-Lys-Lys-Pro-His-Lys(Biotin)-NH2N/A
  • Adrenocorticotropic Hormone (ACTH) (1-10), humanAdrenocorticotropic Hormones (ACTH). ACTH stimulates the adrenal cortex and the secretion of glucocorticoids such as cortisol. Another name for ACTH is corticotropin.
  • Adrenocorticotropic Hormone (ACTH) (1-39), ratPeptide fragments of ACTH (1-39) were formed during in vitro incubation of the peptide with membrane preparations. ACTH (1-39) were isolated by high pressure liquid chromatography, and peptide fragments of ACTH (1-39) characterized by determination of amino acid composition and NH2- terminal residue.
  • Adrenocorticotropic Hormone (ACTH) (18-39), humanAdrenocorticotropic hormones ACTH. ACTH stimulates the adrenal cortex and the secretion of glucocorticoids such as cortisol. Another name for ACTH is corticotropin.
  • Adrenocorticotropic Hormone (ACTH) (4-10), humanAdrenocorticotropic Hormones (ACTH). ACTH stimulates the adrenal cortex and the secretion of glucocorticoids such as cortisol. Another name for ACTH is corticotropin.
  • Adrenomedullin (AM) (22-52), humanAM (22-52) is known as an adrenomedullin receptor antagonist and a cardiac depressant factor, although there is some discrepancy in the literature regarding the selectivity of ADM 22-52 as adrenomedullin receptor antagonist.
  • AGRP (87 - 132), humanThe cysteine-rich C-terminal domain of AGRP, corresponding to AGRP(87-132), exhibits receptor binding affinity and antagonism equivalent to that of the full-length protein.
  • Amylin, human, amideAmylin, a 37-amino acid polypeptide that is structurally related to calcitonin, is secreted from the B cells of the pancreas. Amylin has anoretic effects in rats. Amylin may be responsible for the etiology of insulin resistance of type II diabetes mellitus through its modulation of peripheral effects of insulin. Amylin blocks the activation of glycogen synthase by insulin.
  • Amylin, amide, ratAmylin is a peptide that displays 50% homology with calcitonin gene-related peptide (CGRP), Amylin is colocalized with somatostatin in endocrine cells of the gastric fundus. In isolated mouse stomach, amylin caused a concentration-dependent decrease in acid secretion. In rat fundic segments, amylin and CGRP each caused a concentration-dependent increase in somatostatin and a decrease in histamine secretion.
  • Angiotensin II (3-8), humanAngiotensin II (AII) (3-8) causes endothelium-dependent renal cortical vasodilatation. Pretreatment with L-arginine reveals AII (3-8)'s vasodilating effects on rabbit pial arterioles. The response to AII (3-8) was unchanged by L-arginine.
  • AMThis peptide consists of two amino acids, Ala and Met, and is provided at >95% purity.
  • AFThis peptide consists of two amino acids, Ala and Phe and is provided at >95% purity.
  • AIThis peptide consists of two amino acids, Ala and Ile, and is provided at >95% purity.
  • ASThis peptide consists of two amino acids, Ala and Ser, and is provided at >95% purity.
  • ATThis peptide consists of two amino acids, Ala and Thr, and is provided at >95% purity.
  • AYThis peptide consists of two amino acids, Ala and Tyr, and is provided at >95% purity.
  • AVThis peptide consists of two amino acids, Ala and Val, and is provided at >95% purity.
  • AKThis peptide consists of two amino acids, Ala and Lys, and is provided at >95% purity.
  • Asp-Asp-Asp-Asp-AspTetraaspartic acid (Asp-Asp-Asp-Asp) is a small polyanionic peptide used in physicochemical studies along with other polyanionic peptides. Tetraaspartic acid forms complexes with metals such as copper making it useful in studies on copper mediated effects such as free radial formation.
  • AGA}{(C8R) HNG17, Humanin derivativeThis peptide is a potent humanin (HN) derivative. It completely suppresses neuronal cell death by Alzheimer's disease-relevant insults.
  • abaloparatideAbaloparatide is an analog of PTHrP (parathyroid hormone-related protein). It was approved in April 28, 2017 by the FDA (as Tymlos) for the treatment of postmenopausal women with osteoporosis at high risk for fracture. Abaloparatide is a synthetic peptide that is related to hPTHrP and has demonstrated in preclinical testing the potential to widen the anabolic window for bone therapeutics, stimulating bone formation with a limited effect on bone resorption and mineral mobilization.
  • Abarelix Abarelix is a potent antagonist, used for prostate cancer treatment.
  • AEZS-108Zoptarelin Doxorubicin is a peptide agonist of the gonadotropin releasing hormone-1 receptor (GnRH-1R) that is conjugated to the anthracycline antibiotic doxorubicin with potential antineoplastic activity. Zoptarelin doxorubicin binds to GnRH-1Rs, which may be highly expressed on endometrial and ovarian tumor cell membrane surfaces, and is internalized. Once inside the cell, the doxorubicin moiety of this agent intercalates into DNA and inhibits the topoisomerase II activity, which may result in the inhibition of tumor cell DNA replication and tumor cell proliferation.
  • AfamelanotideAfamelanotide is an analog of the peptide hormone alpha-melanocyte stimulating hormone (alpha-MSH) that tends to induce skin tanning. It is being developed by the Australian company Clinuvel Pharmaceuticals (previously known as EpiTan). Afamelanotide was approved in Europe in October, 2014 for the treatment of erythropoietic protoporphyria (EPP).
  • Alanyl GlutamineAlanyl Glutamine is under investigation in clinical trial NCT00338221 (Clinical Trial of Alanyl-Glutamine or Glycine in Children With Persistent Diarrhea or Malnutrition).
  • AlbiglutideAlbiglutide is a glucagon-like peptide-1 agonist (GLP-1) biologic drug indicated in the treatment of type 2 diabetes. It is marketed under the brands Eperzan and Tanzeum by GSK (GlaxoSmithKline). It is a dipeptidyl peptidase-4-resistant glucagon-like peptide-1 dimer fused to human albumin.
  • AmbamustineAmbamustine is a tripeptidic nitrogen mustard compound and bifunctional alkylating agent with antineoplastic activity.
  • Anaritide acetateAntihypertensive, Diuretic, Vasodilator, Atrial natriuretic peptide receptor agonist.
  • Angiotensin 1 Human Angiotensin 1 (Human) is the precursor to the vasoconstrictor peptide angiotensin II, cleaved by the angiotensin-converting enzyme (ACE).
  • Angiotensin 1-7 Angiotensin (1-7) inhibits purified canine angiotensin converting enzyme activity with an of 0.65 μM.
  • AnidulafunginAnidulafungin was previously known as LY303366. There is preliminary evidence that it has a similar safety profile to caspofungin.
  • AP-17444N/A
  • AP214AP214 is being developed for protection of kidney injury in patients undergoing cardiac surgery under cardiopulmonary bypass as the lead indication.
  • Apistoxin InjectionN/A
  • AplidinPlitidepsin (also known as dehydrodidemnin B) is a chemical compound extracted from the ascidian Aplidium albicans. It is currently undergoing clinical trial testing. It is a member of the class of compounds known as didemnins.plitidepsin exhibits antitumor, antiviral and immunosuppressive activities. It shows promise in shrinking tumors in pancreatic, stomach, bladder, and prostate cancers.
  • Aprotinin Aprotinin is a inhibitor isolated from bovine lung which inhibits trypsin and chymotrypsin with values of 0.06 pM and 9 nM, respectively.
  • ARA290 ARA290 is an EPO-derivative, acting as a specific agonist of erythropoietin/CD131 heteroreceptor, and used for neurological disease treatment.
  • Arenicin21 amino acids; rich in arginine and hydrophobic amino acids.
  • ATN-161ATN-161 is a non-RGD based integrin binding peptide targeting alpha-5 beta-1 and alpha-v beta-3. It inhibits the migration and adhesion of particular integrins on activated endothelial cells that play a critical role in tumor angiogenesis. This approach targeting both the tumor vasculature and the cancer cells themselves, may be effective in single therapy as well as combination therapy.
  • AtosibanAtosiban is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. Although initial studies suggested it could be used as a nasal spray and hence would not require hospital admission, it is not used in that form.
  • Aureobasidin ABasifungin is an orally available cyclic depsipeptide antibiotic produced by Aureobasidium pullulans that is a fungicide at low concentrations. Aureobasidin A inhibits inositol phosphorylceramide synthase, an enzyme that catalyzes a key step in fungal sphingolipid biosynthesis. This may inhibit fungal cell growth.
  • Auristatin PESoblidotin is a dolastatin-10 derivative. Soblidotin inhibits tubulin polymerization, resulting in cell cycle arrest and induction of apoptosis.
  • Avidocin and purocinModified R-type bacteriocins from Pseudomonas aeruginosa.
  • AZP-531 AZP-531 is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight.
  • AZX100AZX100 is a synthetic 24 amino acid peptide in the field of smooth muscle relaxation and fibrosis. Signaling pathways for actin-mediated smooth muscle relaxation converge by activating a protein called heat shock related protein 20 (HSP20). AZX-100 is a cell permeant peptide that mimics HSP20, bypassing the signaling pathways leading to smooth muscle relaxation. This mechanism of action is particularly important in certain patients, such as asthmatics with mutations in the β-receptor (β16 Arg/Arg genotype) or in some forms of vasospasm (such as subarachnoid hemorrhage induced vasospasm which leads to strokes).
  • Ac-DEVD-AFC Ac-DEVD-AFC is a fluorogenic substrate (λ=400 nm, λ=530 nm).
  • Ac-DEVD-AMCAc-DEVD-AMC is a fluorogenic substrate that can be cleaved specifically by caspase-3.Caspase activity can be quantified by fluorescent detection of free AMC (also known as 7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm.
  • Ac-DEVD-CHO Ac-DEVD-CHO is a specific inhibitor with a value of 230 pM.
  • Ac-Gly-BoroPro Ac-Gly-BoroPro is a selective inhibitor with a of 23 nM.
  • Ac-Leu-Arg-AMC Ac-Leu-Arg-AMC is a fluorogenic peptide substrate.
  • ACTH 11-24 ACTH (11-24) is a fragment of adrenocorticotrophin, acts as an antagonist of , and induces cortisol release.
  • ACTH 1-13 ACTH (1-13) is a 13-aa peptide, with cytoprotective effects in the model of ethanol induced gastric lesions in rats.
  • ACTH 1-14 ACTH (1-14) is a fragment of adrenocorticotrophin, which regulates cortisol and androgen production.
  • ACTH 22-39 ACTH (22-39) is an adrenocorticotropic hormone (ACTH) fragment. ACTH (22-39) is the 22-39 sequence of ACTH.
  • ACTH 4-11 ACTH (4-11), an adrenocorticotropin hormone fragment, possesses a weak α-melanocyte stimulating hormone (α-MSH) potency only at high doses (100 and 1000 nM).
  • Adipokinetic Hormone (AKH) (24-32), locust Adipokinetic Hormone (AKH) (24-32), locust is a peptide hormone isolated from .
  • Adrenorphin Adrenorphin is a opioid octapeptide, acting as a potent agonist of , with of 12 nM.
  • Alexamorelin Alexamorelin is a new synthetic heptapeptide which inhibits binding in vitro.
  • Alexamorelin Met 1 Alexamorelin Met 1 is one of the metabolites of alexamorelin. The heptapeptide Ala-His--2-methyl-Trp-Ala-Trp--Phe-Lys-NH (Alexamorelin) is a synthetic molecule which inhibits growth hormone secretagogue binding .
  • Alisporivir intermediate-1 Alisporivir intermediate-1 is an intermediate in the synthesis of Alisporivir. Alisporivir is used for the treatment of inflammatory and viral diseases.
  • ALX 40-4C ALX 40-4C is a small peptide inhibitor of the that can inhibit X4 strains of HIV-1; ALX 40-4C also acts as an antagonist of the , with an of 2.9 μM.
  • ALX 40-4C Trifluoroacetate ALX 40-4C Trifluoroacetate is a small peptide inhibitor of the that can inhibit X4 strains of HIV-1; ALX 40-4C Trifluoroacetate also acts as an antagonist of the , with an of 2.9 μM.
  • Amylin (8-37), rat Amylin (8-37), rat is a truncated analog of native Amylin that selectively inhibits insulin-related glucose uptake and glycogen deposition in muscle tissue. Amylin (8-37), rat is a weak antagonist.
  • Amyloid beta-peptide(25-35) Amyloid beta-peptide(25-35) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide, has shown neurotoxic activities in cultured cells.
  • Amyloid β-Protein 10-20 Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.
  • Angiogenin 108-122 Angiogenin (108-122) is an angiogenin peptide.
  • Angiotensin II 5-valineAngiotensin II 5-valine is an agonist of angiotensin receptor.
  • Angiotensin III, human, mouse Angiotensin III, human, mouse is a heptapeptide, acts as an endogenous agonist, with s of 0.648 nM and 21.1 nM for ATR and ATR, respectively.
  • Antennapedia Peptide Antennapedia Peptide is a 16 amino acid peptide, originally derived from the 60 amino acid long homeodomain of the Drosophila transcription factor Antennapedia and is a member of the family of Cell-penetrating peptides.
  • Autocamtide-2-related inhibitory peptide TFA Autocamtide-2-related inhibitory peptide (TFA) is a highly specific and potent inhibitor of with an of 40 nM.
  • Ac-IEPD-pNAN/A
  • Ac-YVAD-CMKCaspase-1 Inhibitor II (Ac-YVAD-CMK) is a cell-permeable and irreversible inhibitor of caspase-1 (Ki = 760 pM), caspase-4, and caspase-5. It also inhibits Fas-mediated apoptosis and acidic sphingomyelinase activation. Caspase inhibitors play an important role in investigating biological processes.
  • Ac-LEHD-CMKThe Caspase-9 Inhibitor III, controls the biological activity of Caspase-9. This small molecule/inhibitor is primarily used for Cancer applications.
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