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  • Cyclo ( - RADfK - )This peptide is a negative control for the cyclo (-RGDfK-), the RGD peptide. RGD peptides are modulators of cell adhesion and are recognized by several members of the integrin family. This peptide has low affinity binding to integrin peptides.
  • Integrin - Binding SiteThis is an integrin-binding peptide.
  • Prototype of RGDThis is a fluorescent (FITC)-labeled Prototype of RGD-containing peptide, Abs/Em=492/516 nm.
  • Integrin Binding PeptideThis is fibronectin derived, integrin-binding peptide. It may be used for PEG hydrogel preparation.
  • [Glu3] - RGES, Control for RGD PeptidesThis peptide is a control for the RGDS Fibronectin Active Fragment and other RGD-related peptides. Asp3 is replaced by Glu3 in RGDS peptide changing its properties to inhibit integrins and proteins of extracellular matrix binding.
  • Cyclo ( - GRGDSP)This cyclic peptide is a potent vasodilator. It is more powerful than the linear GRGDSP (Cat# 22945, 22946) in changing the vascular tone of arterioles isolated from rat cremaster muscle.
  • Cyclo ( - RGDfK)In one study where this peptide was labeled with 125I, it was found to bind specifically and with high affinity to αvβ3 receptors on neovascular blood vessel sections of different major human cancers. The integrin alpha(IIb)beta(3)-specific cyclic hexapeptide contains an Arg-Gly-Asp (RGD) sequence.
  • Cyclo (RGDfC)This is a cyclic RGDfC sequence, an integrin avb3-affine peptide.
  • GRGDS, LC - biotin labeledThe GRGDS peptide contains the amino acid sequence Arg-Gly-Asp (RGD), which has been implicated as a recognition site in interactions between extracellular matrix (ECM) molecules and cell membrane receptors. RGD-containing synthetic peptides are known to inhibit attachment of endothelial cells to substrates. GRGDS peptide inhibits angiogenesis in serum-free collagen gel culture. This synthetic peptide mimics the cellular binding site of many adhesive proteins in the extracellular matrix and causes rounding and detachment of spread cells. This peptide is biotinylated through 6-aminohexanoate (LC) as a spacer.

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